血红蛋白转啊转
生化是音乐区
有关生化的音乐创作不仅多还洗脑。。。
Hemoglobin’s moving around是Oregon State University的生化教授Kevin Ahern根据”Santa Claus is Coming to Town”的旋律填词创作的。
https://www.youtube.com/watch?v=GhP6uNOUeYM
旋律很好听，点击链接被洗脑欣赏
原歌词及翻译：
A metabolic melody by Kevin Ahern (To the tune of “Santa Claus is Coming to Town”) Vocal by Tim Karplus
Oh isn’t it great
蛋白质真厉害
What proteins can do
能做很多事
Especially ones that bind to O2
特别是那些运输氧气的
Hemoglobin’s moving around
血红蛋白转啊转
Inside of the lungs
在我们的肺里
It picks up the bait
它载上某些分子
And changes itself from T to R state
从T态变成R态
Hemoglobin’s moving around
血红蛋白转啊转
The proto-porphyrin system
原卟啉环上
Its iron makes such a scene
铁离子在刷存在感
Arising when an O2 binds
结合氧气时挪一下
Pulling up on histidine
还拉上组氨酸
The binding occurs cooperatively
结合是协同的
Thanks to changes qua-ter-nar-y
因为四级结构的改变
Hemoglobin’s moving around
血红蛋白转啊转
It exits the lungs
它满载氧气
Engorged with O2
从肺中离开
In search of a working body tissue
要找在代谢的身体组织
Hemoglobin’s moving around
血红蛋白转啊转
The proton concentration
氢离子浓度
Is high and has a role
也有影响
Between the alpha betas
在α和β链之间
It finds imidazole
氢离子找到了咪唑环
To empty their loads
为了清空负载
The globins decree
它们决定
“We need to bind 2,3BPG”
“我们要带上2,3BPG”
Hemoglobin’s moving around
血红蛋白转啊转
The stage is thus set
就这样万事俱备
For grabbing a few
Cellular dumps of CO2
为了抓住细胞丢弃的二氧化碳
Hemoglobin’s moving around
血红蛋白转啊转
And then inside the lungs it discovers ox-y-gen
然后在肺里它又发现了氧气
And dumps the CO2 off
就丢下二氧化碳
To start all o’er again
重新再来
So see how this works
要知道这是怎么运作的
You better expect
最好是
To have to describe the Bohr effect
用玻尔效应描述
Hemoglobin’s moving around
血红蛋白转啊转
翻译贡献者：所以我放弃了A